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The Herbal Life
by Braddock Ray


Protect Against Toxins
Take milk thistle for liver health
ÒOur modern environment is full of stressful chemicals [including] food additives and pesticides. These chemicals need to be processed by the liver so that they can be eliminated,Ó explains third-generation herbalist Christopher Hobbs, LAc. ÒFurthermore, the liver is an important organ in the digestion of fat, which is usually overabundant in the modern diet.Ó

Interestingly, milk thistle lowers cholesterol and even helps turn LDL (bad) cholesterol into HDL (good) cholesterol. This herb not only prevents cholesterol from turning into artery-blocking plaque but also lowers the cholesterol content of bile, reducing the chance that gallstones will form.

An Ancient Plant
Used for more than 2,000 years for liver ailments, milk thistle (Silybum marianum) seed has long been revered for its healing power. In ancient Greece, the herbalist Dioscorides advised drinking a tea of milk thistle seeds for snake bite. In England, milk thistle was recommended for melancholyÑand even the plague. Native Americans used this plant as a remedy for boils and skin disorders.

Investigated by Research
With approximately 50 clinical studies in Germany alone, milk thistle is a well-documented treatment for liver problems. ÒItÕs a great free-radical scavenger,Ó finds medical herbalist Donald R. Yance, Jr., AHG, Òand it protects the liver against damage caused by drugs and heavy metals.Ó A variety of pharmaceutical medications from acetaminophen and antidepressants to statin drugs (increasingly prescribed for people with high cholesterol) can also harm the liver.

ÒMilk thistle seeds, as well as turmeric, show great liver-protective effects against a number of toxins, including many chemotherapies,Ó he adds. A flavonoid in milk thistle, silymarin augments the antioxidant action of glutathione, enhancing the liverÕs detoxification capacity. Silymarin also protects liver cell membranes by keeping toxins out of the cells themselves. Perhaps most important of all, this flavonoid stimulates the liverÕs ability to regenerate itself.

One human trial suggests that silymarin blocks fibrosis of the liver, resulting from alcohol abuse (the primary cause of liver disease in this country) and viral hepatitis. Silymarin appears to lessen damage to the liver from hepatitisÑwithout stimulating the growth of cancer cellsÑespecially important since this disease is associated with a greater risk for liver cancer. ÒEvery person with hepatitis C should consider silymarinÓ for long-term treatment, recommends Donald J. Brown, ND.

Other research suggests that milk thistle may relieve inflammation in rheumatoid arthritis. Also effective for acne, psoriasis, and shingles, this herb may even help relieve premenstrual tension.

How to Use Milk Thistle
Because silymarin is not particularly soluble in water, concentrated extracts are advised instead of teas. Most clinical research on milk thistle is based on concentrated extracts, standardized to 70 percent silymarin.

Dr. Brown recommends that anyone with liver diseaseÑor who needs extra liver protection from alcohol, drugs, or synthetic chemicalsÑtake 420 mg of milk thistle extract in three divided doses daily. Individuals with chronic liver disease need to verify milk thistleÕs effectiveness periodically with lab testing. While both clinical experience and research suggest that improvement may occur as early as eight weeks, no one should ever attempt to self-diagnose or treat liver disease.

There are no known contraindications or drug interactions with milk thistle. A small clinical study on milk thistle shows no effect on the immunodeficiency drug indinavir, even though other herbal remedies have produced drug interactions.

This herb even appears safe for pregnant women and nursing mothers, although it may reduce the effectiveness of birth control pills. A few people have occasionally reported a mild laxative effect with milk thistle, but this usually lasts only two to three days.

France, Germany, and Italy are only some of the countries that have approved the use of milk thistle as a drug. However, this detoxifying herb remains a dietary supplement in the U.S., even though no pharmaceutical equivalent exists for milk thistle.

SELECTED SOURCES
- The ABC Clinical Guide to Herbs, Mark Blumenthal, editor ($49.95, Thieme, 2003)
- ÒEffects of Milk Thistle on the Immunodeficiency Drug IndinavirÓ by S. C. Piscitelli et al., Pharmacotherapy, 2002
- Natural Therapy for Your Liver by Christopher Hobbs, LAc ($9.95, Penguin Group/Avery, 2002)
- Prescription for Herbal Healing by Phyllis A. Balch, CNC ($23.95, Penguin Group/Avery, 2002)
- ÒSilymarin from Milk Thistle Demonstrates Selective Experimental Anti-inflammatory Action...Ó by Heather S. Oliff, PhD, HerbClip, 2/6/01

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